Updated July 1, 2025


A 3D-rendered topographic map of Mississippi in green and orange gradients, with raised elevation features and river basins. The foreground displays the bold, white title: "Mississippi Cannabis Tax Guide".

Key Points

  • No Adult‑Use Program Yet
    Mississippi has not legalized recreational cannabis as of 2025, so no excise tax or sales tax applies to adult‑use products.

  • 5 % Excise Tax on Cultivators
    All medical cannabis cultivators owe a 5 % excise tax on their first sale or transfer of flower or trim to a dispensary or related entity.

  • 7 % State Sales Tax at Dispensaries
    Dispensaries must collect the standard 7 % state sales tax at the point of sale; Jackson and Tupelo may impose additional local levies.

  • Mandatory Seed‑to‑Sale Tracking
    Every licensee must use the statewide seed‑to‑sale system maintained by the Department of Health for inventory control and tax reporting.

  • Monthly E‑Filing Required
    All cannabis‑related taxes (excise and sales) must be filed electronically on a monthly basis—even if you report zero sales.

  • Penalties for Noncompliance
    Late filings, unpaid tax, or failures in tracking can trigger fines, interest, audits, license suspension, or revocation.


1. Excise Tax

  • Rate & Applicability
    5 % of the sales price (or fair‑market value, if there is common ownership) on the first sale or transfer from a cultivation facility to a medical cannabis establishment.

  • Who Pays
    Only cultivators pay this excise tax; dispensaries and patients are exempt.

  • Fair‑Market Value Notices
    MDOR publishes fair‑market values twice a year (effective July 1–Dec 31, Jan 1–June 30) to calculate excise tax when entities share ownership.


2. Sales Tax

  • State Rate
    7 % applies to all retail medical cannabis sales.

  • Local Add‑Ons
    Jackson and Tupelo may impose special sales‑tax levies in addition to the 7 % state rate Flowhub.

  • Exemptions
    No sales tax applies to transfers between licensees or to non‑cannabis items sold by dispensaries.


3. Reporting & Filing

  • Frequency: Monthly (20th day of the following month).

  • Method: Electronic filing via TAP (Taxpayer Access Point).

  • Zero‑Sales Filings: Still required to maintain compliance.

  • No Quarterly Option: Cannabis taxes must be filed monthly.


4. Record‑Keeping & Tracking

  • Seed‑to‑Sale:

    • Enter daily inventory, harvests, transfers, sales, disposals, remediation, and ending inventory in the state’s tracking system.

    • Retain backup records for audits.


5. Penalties & Audits

  • Late Filing/Penalties: Late fees, interest, and administrative penalties apply.

  • License Risk: Repeated or egregious noncompliance can lead to suspension or revocation.

  • Audit Exposure: MDOR and Department of Health conduct routine and ad‑hoc audits.


6. Key Industry Associations


7. Government Contacts

Mississippi Department of Health – Medical Cannabis Program

  • Phone: (601) 206-1540

  • Address: 570 E. Woodrow Wilson Ave., Jackson, MS 39216

  • Patients, caregivers or practitioners: MCRegistration@msdh.ms.gov

  • Work permits (agents) or business licenses (cultivation, processing, disposal, commercial transportation, testing facilities): MCLicensing@msdh.ms.gov
  • E-mail updates about the Mississippi Medical Cannabis Program: Subscribe

Mississippi Department of Revenue

  • Cannabis Taxes Website: industry-specific tax information.

  • Phone: (601) 923‑7700

  • Administers: Excise tax, sales tax, income tax.


8. Quick‑Reference Tax Calendar

Tax Type Rate/Details Applies To Filing Due
Excise Tax 5 % of first sale/transfer (or FMV if common ownership) Cultivators 20th, monthly
State Sales Tax 7 % state + any local levies Dispensaries 20th, monthly
Medical Exemptions Cultivator-to-dispensary transfers; patient sales exempted Patients & dispensaries n/a

Disclaimer: This guide is informational only. Always verify rates, deadlines, and procedures with the Mississippi Department of Revenue and Mississippi Department of Health before making compliance decisions.